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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS17
All Species:
18.18
Human Site:
S616
Identified Species:
50
UniProt:
Q8TE56
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE56
NP_620688.2
1095
121127
S616
C
Q
A
H
D
R
L
S
P
K
K
K
G
L
L
Chimpanzee
Pan troglodytes
XP_510617
1095
120963
S616
C
Q
A
H
D
R
L
S
P
K
K
K
G
L
L
Rhesus Macaque
Macaca mulatta
XP_001082280
1095
120948
S616
C
Q
A
H
D
R
L
S
T
K
K
K
G
L
L
Dog
Lupus familis
XP_545825
1181
130543
S699
C
Q
T
H
D
R
L
S
N
K
K
K
G
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P59509
1210
134542
Y709
A
Y
S
V
R
T
S
Y
P
K
H
A
L
Q
W
Rat
Rattus norvegicus
Q1EHB3
1595
175796
Y594
S
Q
F
D
S
M
L
Y
K
G
K
L
H
K
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508084
930
104524
V459
G
K
E
S
P
V
L
V
A
D
R
V
L
D
G
Chicken
Gallus gallus
XP_413886
1086
121805
T610
C
Q
A
H
D
R
Y
T
N
K
K
K
S
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923204
1116
124633
R632
D
F
D
S
L
P
F
R
G
K
Y
Y
N
W
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.3
87.4
N.A.
51.6
26.2
N.A.
60.8
80.4
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
99
89
N.A.
66.2
38.2
N.A.
70.3
86.9
N.A.
47.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
13.3
20
N.A.
6.6
73.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
20
20
N.A.
20
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
45
0
0
0
0
0
12
0
0
12
0
0
0
% A
% Cys:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
12
56
0
0
0
0
12
0
0
0
12
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
12
12
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
12
12
0
0
45
0
12
% G
% His:
0
0
0
56
0
0
0
0
0
0
12
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
12
78
67
56
0
12
12
% K
% Leu:
0
0
0
0
12
0
67
0
0
0
0
12
23
56
56
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
23
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
12
12
0
0
34
0
0
0
0
0
0
% P
% Gln:
0
67
0
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
12
56
0
12
0
0
12
0
0
0
0
% R
% Ser:
12
0
12
23
12
0
12
45
0
0
0
0
12
0
0
% S
% Thr:
0
0
12
0
0
12
0
12
12
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
12
0
12
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
23
% W
% Tyr:
0
12
0
0
0
0
12
23
0
0
12
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _